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PAMAS SVSS
Laboratory particle counter for aqueous fluids with precise flow control for contamination monitoring, size distribution analysis and component cleanliness control
The system PAMAS SVSS is a standard laboratory particle counter for pharmaceutical applications (control of parenterals, infusion solutions, ophtalmic & oral fluids) and other low-viscous liquids. The instrument may be used as “stand alone” or software controlled.
A stepper-motor-actuated precision syringe moves the sample through the laser-diode sensor at the optimum flow-rate and an accurate sample volume is achieved. Using interchangeable syringes, the PAMAS SVSS can analyse sampling volumes of different sizes, from 100 µl to 1000 ml. For small volumes, a special “Small Volume Kit” is available.
The system can be used with different light extinction sensors. The standard sensor PAMAS HCB-LD-50/50 is equipped with a flow-rate of 10 ml/min and a size range of 1 to 200 µm.
Applications
- Parenterals according to common pharmacopoeias
- Water
- Suspensions
- Cleaning solvents
Product features
- Customisable measurement settings
- 16 freely adjustable
- size channels (32 channels upon request)
- Integrated magnetic stirrer
- Use of any sample vessel
- Measuring volume of 100 µl to 1000 ml
- Automatic sample flow and volume control via a stepper motor driven syringe module
- Interchangeable syringes with 1 ml, 10 ml and 25 ml volume
Standards and methods
| ISO 21501-3 | ISO 21501-2 | USP <1788> | ASTM D7647 | USP <787>** | USP <788>** ISO 11500 | |
| USP <789>** | Ph. Eur. 2.9.19** | JP XVI** | KP X** | IP 2.5.8** | BP XIII** |
**in connection with PAMAS USP software
Volumetric sensors
PAMAS HCB-LD-50/50
Available size ranges:
1–200 µm (ISO 21501-3)
1–400 µm (ISO 21501-3) option on request
Max. particle concentration: 24,000 p/ml at 10 ml/min
PAMAS HCB-LD-25/25
Available size ranges:
1–200 µm (ISO 21501-3)
Max. particle concentration: 120,000 p/ml at 10 ml/min
PAMAS SLS-25/25
Available size ranges:
0.5–20 µm (ISO 21501-2)
Max. particle concentration: 13,000 p/ml at 10 ml/min
Software
PAMAS USP for pharmaceutical applications (compliant with 21 CFR Part 11)
PAMAS PMA for contamination control of clean liquids
